It's probably the most significant thing that's happened in my lifetime.
He didn't see it happening in his lifetime, maybe not ever.
So maybe something bad's going to happen in our lifetime.
But this will not happen in my lifetime, I fear.
This is an opportunity to see something that may never happen again in my lifetime.
He had never dreamed this would happen in his lifetime.
We didn't know if it would happen in our lifetime.
I've been afraid of this, but I didn't really believe it would ever happen in my lifetime.
I just don't expect it to happen in my lifetime.
He did not expect to see anything like this happen in his lifetime.