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In reality various effects overlap, including haemodilution or application of high doses of parenteral anticoagulants.
A Saprolegnia infection is usually fatal, eventually causing haemodilution, though the time to death varies depending on the initial site of the infection, rate of growth and the ability of the organism to withstand the stress of the infection.
Before we look at the main issue, hemodilution let us take a brief history into the use of blood.
Some doctors also use hemodilution, which involves taking out blood in advance and replacing it with another fluid, like saline solution.
A range of Hi and Hm was evaluated to understand conditions where hemodilution is necessary to benefit the patient.
There is however the hypervolemic hemodilution (HVH).
Colloids preserve a high colloid osmotic pressure in the blood, while, on the other hand, this parameter is decreased by crystalloids due to hemodilution.
The hemodilution caused by volume expansion with dextran use improves blood flow, thus further improving patency of microanastomoses and reducing thrombosis.
In 1989 The Watchtower stated, "Each individual must decide" whether to accept hemodilution and autologous blood salvage (cell saver) procedures.
Redistribution (hemodilution [as in pregnancy], increased vascular permeability or decreased lymphatic clearance)
Clearly the greater the Hi and the greater the amount of units removed during hemodilution, the more effective ANH is for preventing homologous blood transfusion.
The model assumes that the hemodilute value to the Hm prior to surgery, therefore the re-transfusion of blood obtained by hemodilution, must begin when SBL begins.
During acute normovolemic hemodilution (ANH) blood subsequently lost during surgery contains proportionally fewer red blood cells per millimetre, thus minimizing intraoperative loss of the whole blood.
Acquired deficiency is found after hemodilution, blood losses and/or consumption such as in trauma patients, during some phases of disseminated intravascular coagulation (DIC), and also in sepsis.
Nazih Zuhdi performed the first total intentional hemodilution open heart surgery on Terry Gene Nix, age 7, on February 25, 1960, at Mercy Hospital, Oklahoma City, OK.
Many doctors view acute normovolemic hemodilution, a form of storage of a patient's own blood, as a pillar of "bloodless surgery" but the technique is not an option for patients who refuse autologous blood transfusions.
Hypothermia therapy for neonatal encephalopathy is the only evidence-supported therapy, but anti-oxidant drugs, control of blood glucose levels, and hemodilution (thinning of the blood) coupled with drug-induced hypertension are some treatment techniques currently under investigation.
Another technique, acute normovolemic hemodilution" involves the collection of a selected calculated volume of autologous blood in collection bags prior to the start of surgery with the simultaneous replacement of an equal volume of asanguinous fluid.
This is based on the assumption that each unit removed by hemodilution has a volume of 450 mL (the actual volume of a unit will vary somewhat since completion of collection as we mentioned is dependent on weight and not volume).