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All cellular blood components are derived from haematopoietic stem cells.
He postulated that haematopoietic stem cells had the potential for treatment of diseases.
All T cells originate from haematopoietic stem cells in the bone marrow.
It postulated existence of haematopoietic stem cells.
Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age.
Signalling of Flt3 is important for the normal development of haematopoietic stem cells and progenitor cells.
The protocols used for the cryopreservation process have largely been adapted from those originally designed for bone marrow haematopoietic stem cells.
Donnelly JP: Infection in the neutropenic and haematopoietic stem cell transplant recipient.
A specialised subset of endothelial cells, haemogenic endothelium has the potential to differentiate into haematopoietic stem cells.
Neural stem cells share many properties with haematopoietic stem cells (HSCs).
Haematopoietic stem cells (HSCs)
Research is focused on four main areas: misfolded proteins and disease, intracellular membrane traffic, autoimmune disease and haematopoietic stem cell biology.
In Toronto, he worked with Ernest McCulloch and James Till, who discovered haematopoietic stem cells.
"Haematopoietic Stem cells Derive Directly From Aortic Endothelium During Development."
Haematopoietic progenitors derived from haematopoietic stem cells populate the thymus and expand by cell division to generate a large population of immature thymocytes.
It has been suggested that this area, in particular the ventral wall of the dorsal aorta, is one of the primary origins of the definitive haematopoietic stem cell.
Specialised endothelial cells on the dorsal aorta of the AGM region, identified as haemogenic endothelium differentiate into haematopoietic stem cells.
Total body irradiation (TBI) is a form of radiotherapy used primarily as part of the preparative regimen for haematopoietic stem cell (or bone marrow) transplantation.
When these special endothelial cells were cultured in vitro, they were able to generate haematopoietic stem cells at a higher rate than cells from a haematopoietic origin.
In France, haematopoietic stem cells derived from human fetal livers (7-12 weeks' gestation) have been transplanted into four unrelated second- and third-trimester fetuses with inherited immunodeficiencies or haemoglobinopathies.
Autologous HSCT requires the extraction (apheresis) of haematopoietic stem cells (HSC) from the patient and storage of the harvested cells in a freezer.
PrP immune cells include haematopoietic stem cells, mature lymphoid and myeloid compartments, and certain lymphocytes; also, it has been detected in natural killer cells, platelets, and monocytes.
Haematopoietic stem cells (HSCs) reside in the medulla of the bone (bone marrow) and have the unique ability to give rise to all of the different mature blood cell types and tissues.
The terminal differentiation of some somatic stem cells has recently been called into question after studies of transplanted haematopoietic stem cells showed the development of myoblasts, endothelium, epithelium and neuroectodermal cells, suggesting pluripotency.
Woessmann W, Peters C, Lenhard M, et al.: Allogeneic haematopoietic stem cell transplantation in relapsed or refractory anaplastic large cell lymphoma of children and adolescents--a Berlin-Frankfurt-Münster group report.
The definition of hematopoietic stem cells has changed in the last two decades.
His research has since focused on hematopoietic stem cell biology.
The first line of therapy is hematopoietic stem cell transplantation.
This function is thought to be related to hematopoietic stem cell renewal.
She is one of the world leaders in the field of hematopoietic stem cell biology.
Article: Hematopoietic stem cell transplantation for people with ß-thalassaemia major.
The hematopoietic stem cell transplant patient represents a unique cohort at this point.
Risk factors include smoking, alcohol consumption and hematopoietic stem cell transplantation.
It has been observed following hematopoietic stem cell transplantation.
Its upregulation has been shown to cause premature aging in hematopoietic stem cells.
Hematopoietic stem cells are found in the bone marrow and give rise to all the blood cell types.
It is now being shown that caspase-3 may play a role in embryonic and hematopoietic stem cell differentiation.
Hematopoietic stem cells generate all the cells of the blood and immune system.
However, no physiologic role for this enzyme in the hematopoietic stem cell population has been identified.
Stages of assessment have been described relative to the hematopoietic stem cell transplant patient (see Table 3).
MYST3 is important for proper development of hematopoietic stem cells.
The new technique would later be called autologous hematopoietic stem cell transplantation.
The latter condition mainly occurs in hematopoietic stem cell transplant recipients.
His work has contributed greatly to the understanding of how a single hematopoietic stem cell can give rise to different specialized blood cells.
A more permanent cure is hematopoietic stem cell transplantation.
This works because the marrow is rich in hematopoietic stem cells, which turn into blood cells.
It is an acquired hematopoietic stem cell disorder.
It is a very efficient inducer of hematopoietic stem cell mobilization in animal and human studies.
Upon birth, umbilical cord blood is taken and used for hematopoietic stem cell transplantation.
GPR56 may play a role in the interactions between bone marrow and hematopoietic stem cells.