guide strand

This strand is known as the guide strand.

It is known as the guide strand, incorporated into the Argonaute protein and leads gene silencing.

However, only one of the two strands, which is known as the guide strand, binds the argonaute protein and directs gene silencing.

Translational repression only requires a partial sequence match between the guide strand and target mRNA.

A 50-base Guide strand was synthesized that consisted of a central 10-base probe sequence flanked by two tracts of 20 adenine residues.

The Daily Guide Strands of a cord by Pastor Simon Bear one another's burdens, and so fulfill the law of Christ.

One of the two strands of each fragment, known as the 'guide strand', is then incorporated into the RNA-induced silencing complex (RISC).

The passenger strand is degraded and the guide strand is incorporated into the RNA-induced silencing complex (RISC).

The dsRNA is then separated into two single-stranded RNAs (ssRNA) - the passenger strand and the guide strand.

The guide strand of the miRNA is then loaded into RNA-induced silencing complex (RISC) and is then able to pair with its target.

RISC uses the bound guide strand to target complementary 3'-untranslated regions (3'UTR) of mRNA transcripts via Watson-Crick base pairing.

These single-stranded RNAs, referred to as guide strands, are incorporated into RNA silencing effectors complexes such as the RNA-induced silencing complex (RISC).

This strand is known as the 'guide strand' and is selected by the argonaute protein, the catalytically active RNase in the RISC complex, on the basis of the stability of the 5' end.

The guide strand tends to be the one whose 5' end is less stably paired to its complement, but strand selection is unaffected by the direction in which dicer cleaves the dsRNA before RISC incorporation.

The most well-studied outcome is post-transcriptional gene silencing, which occurs when the guide strand pairs with a complementary sequence in a messenger RNA molecule and induces cleavage by Argonaute, the catalytic component of the RISC complex.

• Second selection: Deadline for submitting the applications: 01/04/2008 Applicant's Guide Strand 1.2.2 Application Package Applicants are requested to read carefully the Specifications and the Applicant's Guide before completing and submitting their applications.

Target sequences of 10 bases containing up to three mismatches were prepared and hybridized to the Guide strand in 1 M KCl. The transport of these constructs through single α-hemolysin pores was analysed by measuring the current blockade as a function of time.