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Another practical application of the compound is its use in gene transfection.
This effect was significantly reduced by IL-10 gene transfection (Fig.
Alone, the IL-10 gene transfection had no effect on MAdCAM-1 expression.
Gene therapy may provide a novel route to introduce new dopamine production via viral-medicated gene transfection, but clinical trials are yet to be completed.
IL-10 gene transfection significantly reduced TK-1 adhesion in response to TNF-α stimulation at 24 h (Fig.
Alone, IL-10 gene transfection did not modify the basal level of lymphocyte adhesion to the endothelium without TNF-α treatment.
Foldamers already have applications as broad-spectrum antibiotics, inhibitors of protein-protein interactions, optical storage materials, gene transfection agents, lung surfactants mimics etc.
Results Secretion of human IL-10 concentration by transfected endothelial cells To screen for the efficacy of IL-10 transfected SVEC, we initially measured the IL-10 concentration in the medium prior to gene transfection.
To maintain the activity of DNA during dehydration, the dendrimer/DNA complexes were encapsulated in a water soluble polymer, and then deposited on or sandwiched in functional polymer films with a fast degradation rate to mediate gene transfection.