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Gastrointestinal stromal tumors can occur in the esophagus and are usually benign.
Gastrointestinal stromal tumors occur most commonly in the stomach.
A clinical trial of targeted therapy (Gleevec) for gastrointestinal stromal tumors.
Gastrointestinal stromal tumors are known to withstand cancer chemotherapy treatment and do not respond to any kind of therapy in advanced cases.
One, called the c-kit receptor, is active in a cancer called gastrointestinal stromal tumor.
Gastrointestinal stromal tumors are rare tumors with malignant potential.
Examples are the published reports on the clinical, pathological and molecular characteristics of the relatively newly recognized gastrointestinal stromal tumors.
Most gastrointestinal stromal tumors express KIT, which can be detected by immunohistochemistry.
It has also secured speedy remissions in some 60 percent of patients with a rare and otherwise deadly stomach cancer known as gastrointestinal stromal tumor.
Gastrointestinal stromal tumor.
Abnormalities of the submucosa, such as gastrointestinal stromal tumors, usually show integrity of the mucosal surface.
Therapy with imatinib can inhibit the non-normal cell signaling mechanisms in gastrointestinal stromal tumors.
Targeted therapy may be used for gastrointestinal stromal tumors that cannot be removed by surgery or that have spread to other parts of the body.
Gleevec, which is used primarily for two obscure cancers - chronic myelogenous leukemia and gastrointestinal stromal tumor - had sales last year of $2.2 billion.
The types of cancer found in the small intestine are adenocarcinoma, sarcoma, carcinoid tumors, gastrointestinal stromal tumor, and lymphoma.
However, tyrosine kinase inhibitor STI571 is effective in the treatment of patients with metastatic gastrointestinal stromal tumors.
How Are Gastrointestinal Stromal Tumors Diagnosed?
Stem cell factor (SCF) receptor (also called c-kit, see the article on gastrointestinal stromal tumor).
But the drug also works in a seemingly unrelated cancer, gastrointestinal stromal tumor, known as GIST, because it has a somewhat similar signaling protein.
ICCs are thought to be the cells from which gastrointestinal stromal tumours (GISTs) arise.
Until the 1990s, all non epithelial tumors of the gastrointestinal tract were called "gastrointestinal stromal tumors" from smooth muscle origin.
Mutation of c-kit causes the constitutive activity of tyrosine kinase which results in cancerous gastrointestinal stromal tumors.
Gastrointestinal stromal tumor (GIST) is the most common form of sarcoma, with approximately 3,000-3,500 cases per year in the United States.
Regorafenib is being studied in Phase 3 trials in demonstrated metastatic colorectal cancer, and gastrointestinal stromal tumors, a rare stomach cancer.