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The anterior end of the hemisphere is named the frontal pole.
Specifically, Addis discovered that the right frontal pole is involved in prospective memory and the construction of future events.
In humans the frontal pole area of the prefrontal cortex includes not only area 10 but part of BA 9.
For him, the prefrontal area was restricted to the anterior-most part of the frontal lobe (approximately corresponding to the frontal pole).
Several studies proposed an association with specific lesions (left anterior and basal ganglia lesions and lesions close to frontal pole) and occurrence of post stroke depression.
The results showed increased activity in the middle frontal gyrus, right putamen, bilaterally in the premotor cortex, in the frontal pole, and bilaterally in the medial insular cortex of the human brain.