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Repeated fractional doses and frequent monitoring by laboratory tests are recommended to minimize the possibility of overdosing.
In general, the higher the daily fractional dose and the greater the amount of tissue that is irradiated, the higher the potential for N&V.
Due to extreme meningitis vaccine shortage, a fractional doses of tetravalent A/C/Y/W135 Meningococcal Polysaccharide Vaccine has been recommended for Africa.
In the present series, there was a low mean age (38.8) at diagnosis, compared with patients with primary linitis plastica (50.5); and all gastric cancers developed in fields previously irradiated with a high dose per fraction, which suggests that a high fractional dose should be regarded as a risk factor for secondary tumours.