foveolar

Foveolar hyperplasia results in large gastric folds.

Thus the foveolar cells can pump out a lot of acid, but acid once in the lumen of the stomach is prevented from returning.

Foveolar cells are also known as surface mucous cells or mucous neck cells, depending on the location.

Foveolar cells are mucus producing cells which cover the inside of the stomach, protecting it from the corrosive nature of gastric acid.

To prevent these disastrous effects, mucus and bicarbonate ions (HCO3-) are secreted by the foveolar cells (also known as mucous cells).

A diagnosis of Menetrier disease should indicate massive overgrowth of mucous cells (foveola) in the gastric mucosa (foveolar hyperplasia) and minimal inflammation.

Type C (chemical) gastritis was characterised by the presence of foveolar hyperplasia and tortuosity, vasodilatation, and congestion with a paucity of inflammatory cells in the lamina propria layer.

There are other cells that secrete mucus (as in the foveolar cells of the stomach), but they are not usually called "goblet cells" because they do not have this distinctive shape.

By contrast type C gastritis is characterised by foveolar hyperplasia and elongation and tortuosity of vessels together with oedema, vasodilatation, and congestion with a paucity of inflammatory cells.

Wu TT, Kornacki S, Rashid A, et al.: Dysplasia and dysregulation of proliferation in foveolar and surface epithelia of fundic gland polyps from patients with familial adenomatous polyposis.