follicular dendritic cell

CD19 is expressed on follicular dendritic cells and B cells.

Polyclonal plasma cells and CD21+ follicular dendritic cells are also seen.

Their origin is uncertain, but they have previously been shown to stain with markers similar to those of follicular dendritic cells, including CD21.

In more conventional paraffin-embedded tissue samples, only the follicular dendritic cells retain the staining pattern.

It is found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets.

Virus particles, coated with antibodies, stick to the follicular dendritic cells, a group of filtering cells that trap foreign material.

Finally, in the last stage of the disease, there is "a virtually complete dissolution of the follicular dendritic cell network," Dr. Fauci said.

It is thought that they may play a role in regulating the germinal center reaction by presenting antigen from the iccosomes of engulfed follicular dendritic cells.

HIV infection induces a state of immune activation leading to loss of follicular dendritic cells and normal lymph node architecture.

Like Dr. Fauci and his colleagues, these investigators found that the AIDS virus coated follicular dendritic cells.

Follicular Dendritic Cell Sarcoma (FDCS) is an extremely rare neoplasm.

The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells.

Autoreactive B cells, maturated coincidentally, normally do not receive survival signals by antigen planted on follicular dendritic cells, and perish by apoptosis.

Activated B-cells migrate from the primary focus of infection into the primary follicles and begin monoclonal expansion in the environment of follicular dendritic cells (FDC).

DNA vaccination generates an effective immune memory via the display of antigen-antibody complexes on follicular dendritic cells (FDC), which are potent B-cell stimulators.

In addition, CD137 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation.

Follicular dendritic cells (FDCs) are cells of the immune system found in primary and secondary lymph follicles of the B cell areas of the lymphoid tissue.

In humans, FDC-SP was first found within follicular dendritic cell isolates from the tonsil, and later was found to be specifically expressed within the periodontal ligament.

Although CR2 is present on all mature B-cells and follicular dendritic cells (FDCs), this only becomes readily apparent when immunohistochemistry is performed on frozen sections.

Follicular dendritic cells and T cells help to select the B-cells that have a high affinity to the antigen for further differentiation into plasma cells and memory cells.

The polymorphous infiltrate consists of lymphocytes of moderate size with pale/clear cytoplasm and smaller reactive lymphocytes, eosinophils, histiocytes, plasma cells, and follicular dendritic cells.

Follicular Dendritic Cells are localized in germinal centers of lymphoid follicles and have an integral role in regulation of the germinal center reaction and present antigens to B cells.

Also, apoptotic chromatin and nuclei may attach to the surfaces of follicular dendritic cells and make this material available for activating other B cells that may have randomly acquired self-specificity through somatic hypermutation.

FO B cells organize into the primary follicles of B cell zones focused around follicular dendritic cells in the white pulp of the spleen and the cortical areas of peripheral lymph nodes.

During this phase of infection, HIV is active within lymph nodes, which typically become persistently swollen, in response to large amounts of virus that become trapped in the follicular dendritic cells (FDC) network.