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It is lined by reticular cells, fibroblasts and fixed macrophages.
Often these cells have specific names depending upon which tissue they settle in, such as fixed macrophages in the liver which become known as Kupffer cells.
The removal of dying cells is, to a greater extent, handled by fixed macrophages, which will stay at strategic locations such as the lungs, liver, neural tissue, bone, spleen and connective tissue, ingesting foreign materials such as pathogens and recruiting additional macrophages if needed.