fibrinolysin

Fibrinolysin and desoxyribonuclease both act as lytic enzymes.

The combination is available as ointment containing 1 BU (Biological Unit) fibrinolysin and 666 BUs desoxyribonuclease per gram.

It does not produce oxidase, coagulase, clumping factor, fibrinolysin, thermostable nuclease, tellurite reductase, gelatinase, protease, urease, arginine dihydrolase, alpha- or beta-haemeolysins, ornithine decarboxylase, acetyl-methylcarbinol or beta-galactosidase.

Plasmin, an effective fibrinolysin produced by tPA or uPA, was thought to be essential in this process, but plasminogen deficient mice do not display major defects of neovascularization in fibrin rich tissues.

Fibrinolysin attacks and inactivates fibrin molecules occurring in undesirable exudates on the surface of the human body and on human mucosa, e.g., in superficial wounds and burns, while desoxyribonuclease targets and destroys (human) DNA.