excitatory amino acid

Glutamate is one of two primary excitatory amino acids, the other being Aspartate.

The compounds, which have yet to be named, appear to block the action of neurotransmitting chemicals in the brain called excitatory amino acids.

An excitotoxic lesion is the process of an excitatory amino acid being injected into the brain using a cannula.

This compound is also routinely used to isolate glutamatergic (excitatory amino acid) receptor function.

The presence of calcium triggers the release of the excitatory amino acid neurotransmitter glutamate.

Kainic acid is an example of an excitatory amino acid used in this type of lesion.

At the annual meeting of the Society for Neuroscience, held in Toronto this month, scientists presented more than 230 papers on excitatory amino acids.

They induced shedding in Xenopus laevis by adding the excitatory amino acid L-aspartate.

The medication phenytoin can also block stress caused to the hippocampus with the help of modulation of excitatory amino acids.

Members of the family include: several mammalian excitatory amino acid transporters, and a number of bacterial transporters.

It acts as an antiexcitotoxic and anticonvulsant, most likely through acting as an antagonist at excitatory amino acid receptors.

Excitatory amino acid transporter 1 (EAAT1)

EAAT4 is expressed predominantly in the retina, has high affinity for the excitatory amino acid L-glutamate.

They are structurally distinct from the second more-restricted family of plasma membrane transporters, which are responsible for excitatory amino acid transport.

DL-threo-beta-benzyloxyaspartate (TBOA) is an inhibitor of the excitatory amino acid transporters.

This gene encodes the excitatory amino acid transporter 1 (EAAT1) protein, which is responsible for glutamate uptake.

Some amines in the chain are pathological; some are normal; some are the endogenous excitatory amino acids transformed into the excitotoxins.

Recent studies from our laboratory have shown that these proteins cause synergistic neurotoxicity that involves excitatory amino acid receptors and oxidative pathways [ 15].

Correlations between clinical pain severity and concentrations of the excitatory amino acid neurotransmitter glutamate within the insular cortex have also been demonstrated using 1H-MRS.

Another type of lesion is excitotoxic lesions that can be caused by excitatory amino acid like kainic acid that kills neuron by stimulating to death.

Once the vesicle is released, glutamate is removed from the synaptic cleft by excitatory amino acid transporters (EAATs).

There are inhibitory amino acids (IAA) or excitatory amino acids (EAA).

As with all NMDA receptor antagonists, dextrorphan and dextromethorphan inhibit the excitatory amino acid and neurotransmitter glutamate in the brain.

Meldrum, B., and J. Garthwaite (1990) "Excitatory Amino Acid Neurotoxicity and Neurodegenerative Disease."