estimated glomerular filtration rate

Many laboratories will also provide the estimated glomerular filtration rate (eGFR).

Time course of changes in renal function as measured by estimated glomerular filtration rate (eGFR)

The serum creatinine concentration can be used to estimate the function of the kidney, called the creatinine clearance or estimated glomerular filtration rate.

Estimated glomerular filtration rate (eGFR)

As a result, gadolinium-containing contrast is now considered contraindicated in patients with an estimated glomerular filtration rate (a measure of renal function) under 60 and especially under 30 ml/mn.

In two Phase 1 trials that included 81 oncology patients, bardoxolone methyl reduced serum creatinine levels, with a corresponding improvement in estimated glomerular filtration rate (eGFR).

In preliminary experiments, this investigational drug was reported to significantly increase estimated glomerular filtration rate (GFR), and improve several other markers of kidney function in patients with chronic kidney disease (CKD).

Data indicate that bardoxolone methyl improves markers of kidney function, including producing a significant increase in estimated glomerular filtration rate that correlates with changes in blood urea nitrogen, serum phosphorus, uric acid, and magnesium.

However, combination therapy, according to the ONTARGET study, is known to worsen major renal outcomes, such as increasing serum creatinine and causing a greater decline in estimated glomerular filtration rate (eGFR).

The estimated glomerular filtration rate (eGFR) should be no lower than 30 mL/min in patients receiving iodinated contrast, and discretion should be used in patients with eGFR less 45 mL/min.

In 2005 the association published, together with the RCP of London, national guidelines on the diagnosis and management of chronic kidney disease (CKD), which led to the routine reporting of the estimated glomerular filtration rate (eGFR) by most National Health Service laboratories.