erythrogenic toxin

Past studies have shown that multiple variants of erythrogenic toxins may be produced, depending on the strain of S. pyogenes present in the host.

A broth culture filtrate from an erythrogenic toxin producing group A streptococci was injected intracutaneously into susceptible persons.

An erythrogenic toxin is a toxin produced by strains of Streptococcus pyogenes, the primary cause of scarlet fever.

Most of the clinical features are caused by erythrogenic toxin, a substance produced by the bacterium Streptococcus pyogenes (group A strep.)

The protein analyzer showed the expected toxins and enzymes being made by the bacteria: Streptolysin O, Streptolysin S, erythrogenic toxin, streptokinase, streptodornase, proteinase.

It carries the speA gene which codes for erythrogenic toxin A. speA is also known as streptococcal pyrogenic exotoxin A, scarlet fever toxin A, or even scarlatinal toxin.

The superantigenic erythrogenic toxin A (ETA) of Streptococcus pyogenes stimulates and amplifies specifically CD4 and CD8 T cells from control donors expressing the V8 and V12 elements.

The erythrogenic toxin is also referred to in the literature as Streptococcal Pyrogenic Exotoxin types A, B, and C (SPE-A, SPE-B, SPE-C).

It is important to recognize that strains of Group A Strep which produce the erythrogenic toxin are not inherently more dangerous than other strains which do not but are more easily diagnosed as such because of the characteristic rash.

Erythrogenic toxin A converts a harmless, nonvirulent strain of Streptococcus pyogenes to a virulent strain through lysogeny, a life cycle which is characterized by the ability of the genome to become a part of and be stably maintained in the host cell for generations.