ergot fungus

He soon began work on the poisonous ergot fungus that grows in grains of rye.

Rye is highly susceptible to the ergot fungus.

Ergot is described botanically as a sclerotium, the form that the ergot fungus takes in winter.

Medicinal usage of ergot fungus began in the 16th century to induce childbirth, yet dosage uncertainties discouraged the use.

Ergothioneine was discovered in 1909 and named after the ergot fungus from which it was first purified, with its structure being determined later, in 1911.

Ergot or ergot fungi refers to a group of fungi of the genus Claviceps.

Claviceps purpurea is an ergot fungus that grows on the ears of rye and related cereal and forage plants.

There are many plant-pathogenic ascomycetes, including apple scab, rice blast, the ergot fungi, black knot, and the powdery mildews.

Some ergoline alkaloids found in ergot fungi are implicated in the condition ergotism, which causes convulsive and gangrenous symptoms.

The presence of ergolines in some species of this family is due to infection by fungi related to the ergot fungi of the genus Claviceps.

The synthetic production of peptide ergot alkaloids using lysergic acid obtained from special cultures of the ergot fungus in tanks has great economic importance.

Ergotamine is a secondary metabolite (natural product) and the principal alkaloid produced by the ergot fungus, Claviceps purpurea, and related fungi in the family Clavicipitaceae.

Early pharmacological testing by Sandoz in laboratory animals showed that LSD can stimulate uterine contractions, with efficacy comparable to ergobasine, the active uterotonic component of the ergot fungus.

The disease cycle of the ergot fungus was first described in 1853, but the connection with ergot and epidemics among people and animals was reported already in a scientific text in 1676.

Ergoline alkaloids (which are ergot alkaloids, named after the ergot fungus, Claviceps purpurea, a close relative of the epichloae) are characterized by a ring system derived from 4-prenyl tryptophan.

Vitamin D is a derivative of ergosterol, a membrane sterol named for the ergot fungus, which is produced by some kinds of phytoplankton, invertebrates, yeasts, and higher fungi such as mushrooms.

It was during his work on the ergot fungus, which grows in rye kernels, that he stumbled on LSD, accidentally ingesting a trace of the compound one Friday afternoon in April 1943.

Drugs derived from natural sources are usually produced by harvesting the natural source or through semisynthetic methods: one example is the semisynthesis of LSD from ergotamine, which is isolated from ergot fungus cultures.

Their beneficent activities attracted generous gifts and endowments, but their income declined significantly after the Reformation, and more particularly once the connection was finally made between St. Anthony's Fire and the ergot fungus, and the incidence of the affliction fell sharply.

Lysergic acid, also known as -lysergic acid and (+)-lysergic acid, is a precursor for a wide range of ergoline alkaloids that are produced by the ergot fungus and found in the Hawaiian Baby Woodrose and the seeds of Morning glory.

Lysergic acid is made by alkaline hydrolysis of lysergamides like ergotamine, a substance usually derived from the ergot fungus on agar plate, or theoretically possible, but impractical and uncommon from ergine (lysergic acid amide, LSA) extracted from morning glory seeds.

Particularly infamous are the lethal amatoxins in some Amanita mushrooms, and ergot alkaloids, which have a long history of causing serious epidemics of ergotism (St Anthony's Fire) in people consuming rye or related cereals contaminated with sclerotia of the ergot fungus, Claviceps purpurea.