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Fibronectin and N-cadherin are key to epithelialization in the developing embryo.
Using an amniotic graft facilitates epithelialization, and has anti-inflammatory as well as surface rejuvenation properties.
HB-EGF is the predominant growth factor in the epithelialization required for cutaneous wound healing.
This is due to an increase in epidermal regeneration and epithelialization in both partial-thickness and full-thickness wounds.
The proliferative phase is characterized by angiogenesis, collagen deposition, granulation tissue formation, epithelialization, and wound contraction.
Features preserved on Doushantuo embryos are compatible with metazoans (animals), but the absence of epithelialization is consistent only with a stem-metazoan affinity.
Keratinocytes themselves also produce and secrete factors, including growth factors and basement membrane proteins, which aid both in epithelialization and in other phases of healing.
Proliferation behind migrating keratinocytes normally begins a few days after wounding and occurs at a rate that is 17 times higher in this stage of epithelialization than in normal tissues.
Chang, W., Gomez, N., and Edelstein, L.M.: Effect of Porcine Xenografts on Epithelialization of donor sites.
Basal keratinocytes from the wound edges and dermal appendages such as hair follicles, sweat glands and sebacious (oil) glands are the main cells responsible for the epithelialization phase of wound healing.
As this primordia begins to undergo epithelialization the anterior portions of the pronephros form rounded protrusions, which then later become the dorsal branches of the pronephros that link to nephrostomes (distinct from nephrotomes).