epigenetically

The state of a cell may be changed epigenetically, in addition to genetic alterations.

However, these genes are epigenetically marked before transmission, altering their levels of expression.

Instead, he suggests that the brain is a selectional system, one in which large numbers of variant circuits are generated epigenetically.

Nucleosomes are thought to carry epigenetically inherited information, as modifications of their core histones.

CC is genetically identical to Rainbow but epigenetically and thus phenotypically different.

Anatomical connectivity in the brain occurs via selective mechanochemical events that take place epigenetically during development.

In contrast, epigenetically mediated gene silencing occurs gradually.

Rather, these are three classes of HSC, each with an epigenetically fixed differentiation program.

"Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli."

If the centromere is inherited epigenetically from one generation to the next, the problem is pushed back to the origin of the first metazoans.

A mutant or epigenetically altered stem cell may replace the other nearby stem cells by natural selection.

Thus, as individuals develop, morphogens activate or silence genes in an epigenetically heritable fashion, giving cells a "memory".

Histones that are methylated on certain residues can act epigenetically to repress or activate gene expression.

The question arises whether there must be still some original way in which the centromere is specified, even if it is subsequently propagated epigenetically.

This is an example of epigenetically modifiable loci called a "metastable epiallele", of which only a few have been identified.

Many miRNAs are epigenetically regulated.

The queen/worker developmental divide is controlled epigenetically by differential feeding with royal jelly; this appears to be due specifically to the protein royalactin.

DNA methylation, specifically hypermethylation, is one of the main ways that the miR-125b1 is epigenetically silenced.

The process involves epigenetically recording the length of cold exposure through chromatin remodeling which leads to mitotically stable changes in gene expression (the "winter code").

DNA methylation patterns can epigenetically affect gene expression in breast cancer and may contribute to some of the observed differences between genetic subtypes.

This is further characterized histologically by the presence of Auer rods and epigenetically by lysine acetylation on residues 24 and 43.

While in patients with AS the maternal Ube3a allele is inactive, the paternal allele is intact but epigenetically silenced.

Intriguingly, both trans-silencer loci, C73 and C97, belong to the 'complex' group, adding weight to the proposition that, like paramutagenicity, trans-silencing activity is encoded epigenetically.

Another putative target is ABL1, which is found activated in hematopoietic malignancies where miR-203 is epigenetically silenced by hypermethylation.

The allele inducing the change is said to be paramutagenic, whilst the allele that has been epigenetically altered is termed paramutant (or paramutated).