epidermodysplasia

Some evidence suggests nonallelic heterogeneity in epidermodysplasia verruciformis.

A character with epidermodysplasia verruciformis was profiled on season 5, episode 20 of Nip/Tuck in 2009.

In very rare cases, HPV may cause epidermodysplasia verruciformis in immunocompromised individuals.

Avoidance of x-ray therapy has also been advocated for some groups with hereditary skin cancer syndromes, such as those with epidermodysplasia verruciformis.

TMC6 and TMC8: Transmembrane channel-like 6 and 8 (epidermodysplasia verruciformis)

In 1972, the association of the human papilloma viruses with skin cancer in epidermodysplasia verruciformis was proposed by Stefania Jabłońska in Poland.

Mutations in either of two adjacent genes on chromosome 17q25 can cause epidermodysplasia verruciformis, a rare heritable disorder associated with increased susceptibility to human papillomavirus (HPV).

Ramoz N, Rueda LA, Bouadjar B, et al.: Mutations in two adjacent novel genes are associated with epidermodysplasia verruciformis.

Jablonska S, Orth G, Jarzabek-Chorzelska M, et al.: Twenty-one years of follow-up studies of familial epidermodysplasia verruciformis.

Epidermodysplasia verruciformis (also called Lewandowsky-Lutz dysplasia) is an extremely rare autosomal recessive genetic hereditary skin disorder associated with a high risk of carcinoma of the skin.

A short video which shows the effects of papillomavirus on the skin of an Indonesian man with epidermodysplasia verruciformis, the genetic inability to defend against some types of cutaneous HPV.

Ramoz N, Taïeb A, Rueda LA, et al.: Evidence for a nonallelic heterogeneity of epidermodysplasia verruciformis with two susceptibility loci mapped to chromosome regions 2p21-p24 and 17q25.

Mutations in the second pair of genes, EVER1 and EVER2 , are linked to epidermodysplasia verruciformis that is associated with an increased susceptibility to infection with some human papillomaviruses causing a high risk of skin carcinoma [ 7 ] .

Mutations in the TMC8 gene are associated with epidermodysplasia verruciformis (EV), an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin.

Majewski S, Hunzelmann N, Nischt R, Eckes B, Rudnicka L, Orth G, Krieg T, Jablonska S.:TGF beta-1 and TNF alpha expression in the epidermis of patients with epidermodysplasia verruciformis.

With Dr. Jadassohn he described an ectodermal dysplasia now known as "Jadassohn-Lewandowsky syndrome", and just prior to his death he described epidermodysplasia verruciformis, a rare skin disease sometimes known as "Lewandowsky-Lutz dysplasia" (named along with dermatologist Wilhelm Lutz 1888-1958).

Inactivating mutations in TMC6 or TMC8 have been implicated as the genetic cause of the rare skin disorder epidermodysplasia verruciformis, which is characterized by abnormal susceptibility to human papillomaviruses (HPVs) of the skin resulting in the growth of scaly macules and papules, particularly on the hands and feet.