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This phenomenon may be important in any application of enterocyte stem cell transplantation.
Once Tir binds intimin, the bacterium is attached to the enterocyte surface.
These then pass from the intestinal lumen into the enterocyte, where they are re-esterified to form triacylglycerol.
Glucose crosses the apical membrane of the enterocyte using the sodium-glucose cotransporter.
Pgp transports lipophilic molecules out of the enterocyte back into the intestinal lumen.
For example, enzymes that digest carbohydrates called glycosidases are present at high concentrations on the surface of enterocyte microvilli.
Once absorbed by the enterocyte, cholesterol is reassembled into large intestinal lipoproteins called chylomicrons.
Fructose, on the other hand, crosses the apical membrane of the enterocyte, using GLUT5.
Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins.
The protein is located in the apical brush-border membrane of the intestinal enterocyte where it regulates calcium entry into the cell.
Vitamin D stimulates absorption of calcium from the GI tract through its interaction with receptors in the enterocyte.
After bowel resection, crypt cell proliferative activity increases, resulting in increased functional enterocyte numbers, which are accommodated by an increase of villus height.
Thus, all this study seems to tell us is that it is rather dangerous to evaluate rectal intraepithelial lymphocytes in terms of enterocyte nuclei (Fig 4).
The antibody selectively binds to oxysterol or oxidized-rich cholesterol micelles and prevents their uptake by the intestinal enterocyte.
A total amount of 15 mg enterocyte protein was coupled to 0.6 g (dry weight) CNBr-activated Sepharose 4B as described above.
Successful clinical application of a treatment entailing transplantation of small intestinal enterocyte stem cells would require a suitable recipient site in which peristalsis is maintained.
Optionally, fragments could be transcytosed across the enterocyte and presented at the basolateral membrane for immunocompetent cells, maybe initiating a pathological response in coeliac patients.
Since copper has a higher affinity for metallothionein than zinc, the copper will remain bound inside the enterocyte, which will be later eliminated through the lumen.
Chylomicrons secreted from the intestinal enterocyte also contain ApoA1 but it is quickly transferred to HDL in the bloodstream.
It moves through the cytosol (cytoplasm) and exits the enterocyte via the basolateral membrane (into the blood capillary) using GLUT2.
In the enterocyte microvillus, the structural core is attached to the plasma membrane along its length by lateral arms made of myosin 1a and Ca binding protein calmodulin.
Elevated cAMP levels stimulate secretion of Chloride ions and water from the enterocyte into the gut lumen, thus causing watery diarrhea.
Mucosal HIV infection, however, is associated with defects in enterocyte maturation and hyporegenerative cillus atrophy which are less pronounced in patients receiving zidovudine.
The locus of enterocyte effacement (LEE) is a moderately conserved pathogenicity island consisting of 35,000 base pairs in the bacteria Escherichia coli genome.
GLUT5 allows for fructose to be transported from the intestinal lumen into the enterocyte by facilitated diffusion due to fructose's high concentration in the intestinal lumen.