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Cancer rarely comes at a good time, but Louise's diagnosis of an endometrial tumor was at the very least inconvenient.
Uterine cancer is a major health concern for women, often occurring in the form of benign fibroids or malignant endometrial tumors.
But studies in the United States, including the 1998 prevention study, showed the endometrial tumors to be uncommon, easy to diagnose early and highly curable.
Conversely in the over expression of miR-129, proliferation of endometrial tumour cells is significantly reduced via the down regulation of Cdk4.
Endometrial stromal sarcoma is a rare endometrial tumor arising from the stroma (connective tissue) of the endometrium rather than the glands.
Despite this, when purely endometrial tumors are compared to MMMTs, the MMMT tumor tends to have a worse prognosis.
Ferreira AM, Westers H, Wu Y, et al.: Do microsatellite instability profiles really differ between colorectal and endometrial tumors?
Malignant transformation can, however, occur and may be associated with a similar tumor outside of the ovary; such tumors are the result of either a second primary or rupture of the primary endometrial tumor.
Malignant mixed Müllerian tumors are rare endometrial tumors which show both glandular (carcinomatous) and stromal (sarcomatous) differentiation - carcinosarcoma behaves similar to a high grade carcinoma, and it is felt to be of epithelial origin rather than true sarcoma.