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But so little is agreed about the cause of the disorder that endogenous opiates may well be involved.
Parts of the brain that release endogenous opiates lighted up.
The endogenous opiates, b-endorphins, are known to have a role in body homeostasis.
Nevertheless, from brain to bowel is something of a comedown for the endogenous opiates.
In both patients naloxone led to great improvement, supporting the idea that endogenous opiates are involved in the condition.
Endogenous opiates, such as endorphins and enkephalins, mediate pain perception in the body.
Mechanism of action may be antagonism to endogenous opiates such as tetrahydropapaveroline, whose production is augmented in the presence of alcohol.
One team of researchers has argued that oxytocin only plays a secondary role in affiliation, and that endogenous opiates play the central role.
The POMC gene codes for endogenous opiates such as β-endorphin and gamma-endorphin.
These plans were aired at a recent conference celebrating the 80th birthday of Hans Kosterlitz, one of the discoverers of endogenous opiates.
One aspect of the gate control operates by use of endogenous opiates of which there are three chemically-defined families, the enkephalins, the dynorphins and the endorphins.
Except some ancient hardwired behavioral patterns buried in my limbic system, triggered by certain visual cues and pheromones . . . and the need to have small explosions of endogenous opiates go off in my brain."
An analgesic effect, mediated in part by nitric oxide as well, through the upregulation of inducible nitric oxide synthase (iNOS), an increase in endogenous opiates, muscarinic cholinergic receptors and serotonin receptors 5-HT1a and 5-HT3, was repeatedly evidenced.
Just as the discovery of the opiate receptors hijacked by drugs like morphine gave us insight into the presence and roles of endogenous opiates, the cannabinoid receptors acted upon by the THC in marijuana have helped identify endocannabinoids, the substances produced by our own body that normally trigger these receptors.