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Normal physiological metaplasia - such as that of the endocervix is highly desirable.
The area adjacent to the border of the endocervix and ectocervix is known as the transformation zone.
Adenocarcinoma can arise from the endocervix, endometrium and extrauterine sites.
The test may also detect infections and abnormalities in the endocervix and endometrium.
The endocervix (more proximal, within the uterus) is composed of simple columnar epithelium.
A Cervical pregnancy is an ectopic pregnancy that has implanted in the uterine endocervix.
On the contrary, fallopian tube epithelium, endometrium and endocervix are related to paramesonephros (Müllerian duct).
The endocervix may be partially sampled with the device used to obtain the ectocervical sample, but, due to the anatomy of this area, consistent and reliable sampling cannot be guaranteed.
In taking a Pap smear, a speculum is used to open the vaginal canal and allow the collection of cells from the outer opening of the cervix of the uterus and the endocervix.
In regards to the cervix, squamous metaplasia can sometimes be found in the endocervix, as it is composed of simple columnar epithelium, whereas the ectocervix is composed of stratified squamous non-keratinized epithelium .