Many people with Type 2 who have not already experienced end-organ damage can be cured by carbohydrate restriction.

If iron overload has caused end-organ damage, this is generally irreversible and may require transplantation.

Thus, if this strategy is to be used, circulatory volume status and end-organ function must be carefully monitored.

During a hypertensive emergency uncontrolled blood pressure leads to progressive or impending end-organ dysfunction.

Acute end-organ damage may occur, affecting the neurological, cardiovascular, renal, or other organ systems.

This process results in end-organ damage due to loss of nutrients, oxygen, and removal of cellular waste products.

Examples of end-organ dysfunction include the following:

This low frequency of end-organ renal damage suggests a potential predisposition to this complication.

Retinitis is the most common clinical manifestation of CMV end-organ disease.

Pulmonary hypertension (PHT) represents an example of such end-organ damage.

Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered.

In type 2 diabetes, insulin production is present but is insufficient to meet the body's requirements as a result of end-organ insulin resistance.

Alcohol related hepatic, pancreatic, gastrointestinal, cardiovascular, or renal disease i.e. other end-organ damage.

More specific definitions of end-organ dysfunction exist for SIRS in pediatrics.

Careful monitoring for signs of end-organ damage or progression to hypertension is an important part of the follow-up of patients with prehypertension.

If the patient's circulatory volume is adequate but there is persistent evidence of inadequate end-organ perfusion, inotropes may be administered.

Third, signs of end-organ dysfunction are required such as renal failure, liver dysfunction, changes in mental status, or elevated serum lactate.

Other end-organ damage can include acute renal failure or insufficiency, retinopathy, eclampsia, and microangiopathic hemolytic anemia.

Detailed Description: As patients with sickle cell disease (SCD) age, recurrent vaso-occlusive episodes lead to progressive end-organ damage.

These patients usually tolerate cytotoxic therapy poorly, with increased morbidity and mortality due to increased infectious complications and often increased end-organ toxicities.

Even in the absence of retinitis with other CMV end-organ disease, periodic ophthalmologic examinations are needed to monitor for cidofovir-associated uveitis when this agent is used.

Failure to receive antibiotic therapy, especially during the initial stages of the disease, may lead to end-organ failure (heart, kidney, lungs, meningitis, brain damage, shock, and even death.

If sepsis worsens to the point of end-organ dysfunction (renal failure, liver dysfunction, altered mental status, or heart damage), then the condition is called severe sepsis.

These studies raise the possibility, therefore, that the appearance or disappearance of a factor or factors in adolescents and adults reduces susceptibility to end-organ injury in HUS.

The morbidity and mortality of hypertensive emergencies depend on the extent of end-organ dysfunction at the time of presentation and the degree to which blood pressure is controlled afterward.

The vestibular end organs have a smaller surface area and are thicker.

The authors suggested that this might represent end organ resistance to growth hormone.

At a short distance, the end organs of the palpi detect the odors.

Subsequent work led to the suggestion that the saccule was the end organ excited.

Post-ganglionic fibres then carry them to the end organs they innervate.

Reduced blood flow due to thrombosis and cellular injury results in end organ damage.

Ruffini's end organs detect tension deep in the skin.

Early treatment is essential to preventing end organ damage, which is often irreversible."

The unusually high density of proprioceptive receptor end organs supports this notion.

Estrogens have positive effects of mood, sexual function, target end organs, and cognitive function.

Evidence of shock (poor end organ perfusion)

Ear, the auditory end organ.

If the falls significantly below this number for an appreciable time, the end organ will not get enough blood flow, and will become ischemic.

In addition, nocturnal hypertension is associated with end organ damage and is a much better indicator than the daytime blood pressure reading.

In fact, the vestibular end organs show no overt morphological defect other than the reduced presence of these immature hair cells.

Ganglionic influence can be specifically targeted to end organs as well as becoming part of a summating systemic response.

End organs feel.

Suspended animation using musculoskeletal paralytic agents will effectively stop the effects of muscular hyperactivity on end organs.

In acute decompensated heart failure, the immediate goal is to re-establish adequate perfusion and oxygen delivery to end organs.

Some patients may develop end organ damage such as bronchiectasis secondary to recurring or chronic infections [66].

No patient had any coexistent illness apart from pulmonary emboli in three cases and secondary end organ dysfunction in four.

The stem cells eventually form enamel, dentin, blood vessels, dental pulp, nervous tissues, including a minimum of 29 different unique end organs.

Ruffini's end organ (sustained pressure)

All IMIDs can cause end organ damage, and are associated with increased morbidity and/or mortality.

Thus, in health, there does not seem to be either an attenuation of secretory pathways mediating gastric acid secretion or end organ resistance to stimulation.