embryotoxicity

It seems likely that warfarin induced embryotoxicity may be due at least in part to this inhibition.

Pregnancy: Animal studies did not reveal any embryotoxicity or fetotoxicity, nor did limited human experience.

It is moderately toxic to animals and has been shown to produce birth defects and embryotoxicity at high doses.

Vanaerts et al. [ 27 ] demonstrated that high concentrations of homocysteine are associated with embryotoxicity during early gestation in rats.

However, data on embryotoxicity in humans are very limited, and it is not clear what the risk for an abortion or for teratogenicity (birth defects) is.

Voriconazole is FDA category D because of cleft palate and renal defects seen in rats and embryotoxicity in rabbits.

Animal experiments have indicated that instant coffee confers no risk related to reproduction, lactation, embryotoxicity or teratogenicity, but possibly a risk of a delay in bone calcification in high doses.