dynamic mutation

The phenomenon is also referred to as anticipation or dynamic mutation.

These are labelled in dynamical genetics as dynamic mutations.

Most other evolutionary games, e.g. resource conflicts, do not need to include this process of dynamic mutation in the analysis of game dynamics itself.

If the repeat is present in a healthy gene, a dynamic mutation may increase the repeat count and result in a defective gene.

This usually leads to new expansions as generations pass (dynamic mutations) instead of reproducing an exact copy of the trinucleotide repeat.

That is, the replication product (progeny) of a dynamic mutation has a different likelihood of mutation than its predecessor.

However, meiotic instability could result in a dynamic mutation that increases the number of repeats in offspring inheriting the mutant allele.

Robert I. Richards and Grant R. Sutherland called these phenomena, in the framework of dynamical genetics, dynamic mutations.

Anticipation is common in trinucleotide repeat disorders such as Huntington's disease and myotonic dystrophy where a dynamic mutation in DNA occurs.

His work focuses on unusual DNA structures and their role in genomic instability, as well as on dynamic mutations, such as Trinucleotide repeat disorders.

In genetics, a dynamic mutation is an unstable heritable element where the probability of expression of a mutant phenotype is a function of the number of copies of the mutation.