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Both serotypes are involved in slightly different drug-sensitive diseases.
Patients with drug-sensitive TB breed drug-resistant organisms if medications are stopped.
Drug-sensitive species and individual humans are initially assumed to lack genes expressing specific drug detoxification enzymes.
Its derivatives, artesunate and artemether, have been used in clinics since 1987 for the treatment of drug-resistant and drug-sensitive malaria, in especially, cerebral malaria.
MDR-TB is spread from person to person as readily as drug-sensitive TB and in the same manner.
Curiously, mutant revertant MCF-7/AdrVp cells that lost their multidrug resistance and became drug-sensitive also lost H19 expression.
The New York City Police Department requires tests when there is reason to suspect an officer of using drugs and when officers are being considered for assignment to narcotics units or other drug-sensitive posts.
TMP-SMX, administered for PCP prophylaxis, and clarithromycin or azithromycin, administered for MAC prophylaxis, are appropriate for drug-sensitive organisms.
TMP--SMX, administered daily for PCP prophylaxis, and azithromycin or atovaquone-azithromycin, administered for MAC prophylaxis, also may reduce the incidence of drug-sensitive serious bacterial infections in children with recurrent serious bacterial infections.
Drug resistance is a growing problem; the WHO has reported that up to 50 percent of people with multidrug resistant TB may die of their infection despite treatment, which can be 10 to 50 times more expensive than that used for drug-sensitive TB.
"The economic and clinical benefits suggested by these reductions may be enhanced by further expansions in prescription drug coverage for seniors, improvements in benefit designs for drug-sensitive conditions, and policies that integrate Medicare payment and delivery systems across drug and nondrug services," write the researchers.