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Drug-induced hepatitis is discussed in a separate section above.
It is also a cause of drug-induced hepatitis.
There can be three types of drug-induced hepatitis.
The single biggest problem with TB treatment is drug-induced hepatitis, which has a mortality rate of around 5%.
Dangerous side effects are drug-induced hepatitis and hepatocellular insufficiency.
Troglitazone (Rezulin), which was withdrawn from the market due to an increased incidence of drug-induced hepatitis.
The clinical course of drug-induced hepatitis is quite variable, depending on the drug and the patient's tendency to react to the drug.
The same scheme as is used for test dosing for drug-induced hepatitis (described below) may be used.
Three different incidents have been reported: one ending in death, one in a liver transplant and one case of drug-induced hepatitis.
The old dose for pyrazinamide was 40-70 mg/kg daily and the incidence of drug-induced hepatitis has fallen significantly since the recommended dose has been reduced.
In the standard four-drug regimen (isoniazid, rifampicin, pyrazinamide, ethambutol), pyrazinamide is the most common cause of drug-induced hepatitis.
In the United States, it was introduced and manufactured by Parke-Davis in the late 1990s, but turned out to be associated with an idiosyncratic reaction leading to drug-induced hepatitis.
Some authorities recommend avoiding PZA in patients with known liver disease, because of the five first-line drugs, PZA has the highest risk of producing drug-induced hepatitis.
Normal 0 false false false MicrosoftInternetExplorer4 Adverse event reports of acute renal failure, deafness, drug-induced hepatitis, exfoliative dermatitis, hypomagnesemia, hyponatremia, idiopathic thrombocytopenic purpura, pancreatitis, autoimmune hemolytic anemia, and cerebrovascular accident were identified.
Liver diseases with similar appearances include Reye's syndrome, drug-induced hepatitis from agents with mitochondrial toxicity, including nucleoside reverse transcriptase inhibitors used to treat HIV, and a rare condition known as Jamaican vomiting sickness which is caused by the eating of the unripened Ackee fruit.