drug discontinuation

This neuromuscular condition can be irreversible (even after drug discontinuation).

Even in remitters, a relapse is often observed following drug discontinuation.

Obtaining an informed consent from the patient before execution of the proposed drug discontinuation and therapy is important.

Patients randomized to dabigatran had fewer minor bleeds, but more dyspepsia and more drug discontinuation.

Chronic administration of the drug has led to occasional instances of cholestatic hepatitis, reversible upon drug discontinuation.

It appears reasonable to reserve steroids for patients with severe systemic SSZ toxicity that fail to respond to supportive care following drug discontinuation.

There has also been evidence of prolonged budiodarone cardiac effect days after drug discontinuation as the atrial fibrillation baseline measurements were not reached in washout periods.

The findings supported the hypothesis that brain regions implicated in depression, with extensive serotonergic innervation, would exhibit changes in activity associated with emergence of symptoms following drug discontinuation.

Due to the infrequent occurrence of severe SSZ toxicity that does not improve with drug discontinuation, it is unlikely that randomized controlled trials of steroids or other interventions will be performed.

Bone marrow biopsy specimens of patients with SSZ induced agranulocytosis reveal a paucity of myeloid cells but full recovery typically occurs within 10 days of drug discontinuation [ 35 36 37 ] .

Drug discontinuation may cause rebound effects (return of the symptoms the drug relieved, and that, to a degree stronger than they were before treatment first began) and withdrawal syndromes (symptoms caused by the discontinuation by the drug itself).