dopaminergic cells

These dopaminergic cells (group A11) project to the spinal cord, and their function is not well established.

Individuals with Parkinson's have a lack of dopaminergic cells which results in the difficulty with movement.

Group A8 is a small group of dopaminergic cells in rodents and primates.

This cell group (A10) is the largest group of dopaminergic cells in the human brain, though still quite small in absolute terms.

These stereotyped inhibitions may have been caused by the removal of central neuronal processes other than the dopaminergic cells in the olfactory tubercle.

MPTP, is a neurotoxin specific to dopaminergic cells in the brain, specifically in the substantia nigra.

The PN and PBP are rich in dopaminergic cells, whereas the other two regions have low densities of these neurons.

Pathologically, it is characterized by the loss of dopaminergic cells of the substantia nigra, pars compacta (SNc).

In dopaminergic cells in the brain, tyrosine is converted to levodopa by the enzyme tyrosine hydroxylase (TH).

For example, Parkinson's disease is at least in part related to failure of dopaminergic cells in deep-brain nuclei, for example the substantia nigra.

Group A9 is the most densely packed group of dopaminergic cells, and is located in the ventrolateral midbrain of rodents and primates.

This theory is supported indirectly by the fact that patients with Parkinson's Disease have an increase in dopaminergic cells in the olfactory bulb and usually exhibit hyposmia.

Gluck and his lab members are studying memory impairments in patients with Parkinson's disease, a condition characterized by the death of dopaminergic cells in the substantia nigra.

Microglia associated with dopaminergic cells in the SN produce quinolinic acid at this location when scientists induce Parkinson's disease symptoms in macaques.

Parkinson's disease involves major loss of dopaminergic cells in the substantia nigra; Huntington's disease involves massive loss of medium spiny neurons in the striatum.

Group A11 is a small group of dopaminergic cells located in the posterior periventricular nucleus and the intermediate periventricular nucleus of the hypothalamus in the macaque.

Much of this evidence stems from investigations manipulating cells in the hippocampus alters dopamine levels in NAcc and firing rates of VTA dopaminergic cells.

Also, the use of embryonic dopaminergic cells cannot be used because these cells are difficult to obtain and modifications of cell can only be made on somatic cells not germline.

The mechanism behind this effect isn't well-understood, but many believe (without clear substantiation) that it selectively kills serotonergic neurons, in a similar way that 6-hydroxydopamine (6-OHDA) is used to kill dopaminergic cells.

Schisandrin B also increases the resistance of dopaminergic cells against paraquat-induced oxidative stress through reducing the extent of oxidant-induced GSH depletion and enhancing the subsequent GSH recovery.

Omigapil also rescues rat oligodendrocytes from AMPA receptor excitotoxicity and rat embryonic mesencephalic (midbrain) dopaminergic cells from toxicity by MPP+/MPTP.

For Parkinson's disease patients, there is a major loss of dopaminergic cells in the substantia nigra, wich is a part of the basal ganglia, and patients have a hard time initiating and balancing their movements.

Since both gp120 and Tat have been shown to cause toxicity to dopaminergic cells and similarly methamphetamine and cocaine also cause toxicity to dopaminergic systems, we characterized the dopaminergic cell types and receptors in our culture system.

MPP+ has quite selective abilities to cause neuronal death in dopaminergic cells, it is presumed through a high-affinity uptake process in nerve terminals normally used to reuptake dopamine after it has been released into the synaptic cleft.

Nair, V.D., K.S. McNaught, J. Gonzalez-Maeso, S.C. Sealfon, and C.W. Olanow, p53 mediates nontranscriptional cell death in dopaminergic cells in response to proteasome inhibition.