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Do not drink alcohol while you are being treated with docetaxel.
Another large advantage of docetaxel was increased quality of life.
Limited data is available for docetaxel use in children with dosage between 55 and 75 mg/m2.
Another trial with docetaxel was recruiting in July 2009.
Together with docetaxel, it forms the drug category of the taxanes.
Oral dexamethasone is given before docetaxel treatment for prostate cancer.
Synthetic approaches to paclitaxel production led to the development of docetaxel.
It will compare calcitriol plus docetaxel to the chemotherapy drug alone in 240 patients.
However, none of the studies reviewed involved a direct comparison between paclitaxel and docetaxel.
In practice, docetaxel is administered intravenously only to increase dose precision.
Taxotere, known generically as docetaxel, aims to be the second drug in this class.
Enhanced effects of radiation therapy when combined with docetaxel has been observed in mice.
Intravenous administration of docetaxel results in 100% bioavailability and absorption is immediate.
The following model is agreed to represent docetaxel clearance in humans:
Renal failure is thought not to be a significant factor for docetaxel dosage adjustment.
Metastatic breast cancer - used in combination with docetaxel, after failure of anthracycline-based treatment.
While in hospital, Megrahi underwent chemotherapy treatment, receiving the drug Docetaxel.
However the effectiveness of docetaxel versus paclitaxel and other taxanes is still controversial.
Paclitaxel or docetaxel may sometimes be added.
Additionally, the optimal scheduling of docetaxel and other taxanes remains unconfirmed.
Median time to progression and median overall survival were also improved with docetaxel.
There have been some promising results from a phase III trial with docetaxel.
Several more recent articles have found "no evidence that regimens containing docetaxel yield greater benefits than those including paclitaxel."
The concentration-time profile of docetaxel was consistent with a three-compartment pharmacokinetic model.
Treatment with docetaxel has the specific outcome of increasing survival time in patients with certain types of cancer.