disseminated coccidioidomycosis

Fluconazole in the treatment of chronic pulmonary and nonmeningeal disseminated coccidioidomycosis.

Combination therapy of disseminated coccidioidomycosis with caspofungin and fluconazole.

Successful treatment of a critically ill patient with disseminated coccidioidomycosis, using adjunctive interferon-gamma.

A case report indicated that voriconazole in combination with amphotericin B as salvage therapy for disseminated coccidioidomycosis was successful.

Extrapulmonary or disseminated coccidioidomycosis.

Disseminated coccidioidomycosis (also known as "Coccidioidal granuloma") is a systemic infection with Coccidioides immitis, in which 15-20% of people develop skin lesions.

Antony S. Use of the echinocandins (caspofungin) in the treatment of disseminated coccidioidomycosis in a renal transplant recipient.

Caspofungin alone successfully treated disseminated coccidioidomycosis in a renal transplant patient intolerant of fluconazole and in persons in whom conventional therapy failed (331,332).

In patients with diffuse pulmonary disease or nonmeningeal disseminated coccidioidomycosis, relapses occur even in patients without HIV infection in 25%--33% of cases (643,644).

In a patient with disseminated coccidioidomycosis, first-line therapy with amphotericin B and caspofungin alone failed to elicit a response, but the patient was then given caspofungin combined with fluconazole, with good results.

Relapse can occur in as many as 33% of patients with disseminated coccidioidomycosis, even in the absence of HIV infection, so lifelong antifungal suppression with either fluconazole or itraconazole is recommended for HIV-infected children who have coccidioidomycosis (AII) (322,324,335--337).

Pleural effusion Relapse of infection Disseminated coccidioidomycosis Coccidioidomycosis meningitis Arthritis Rash Empyema Bronchopleural fistula Lung scarring (fibrosis) Lung cavities Call for an appointment with your health care provider if coccidioidomycosis symptoms worsen or do not improve with treatment.