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The compound is a dinucleotide, since it consists of two nucleotides joined through their phosphate groups.
Modifications at the 5' end of the dinucleotide initiator produces fluorescent abscripts.
Nicotinamide adenine dinucleotide has several essential roles in metabolism.
The statistical problem is to test the hypotheses that patterns of dinucleotide over- and under-representation in a given genome are invariant.
In human and mouse, CGs are the least frequent dinucleotide, making up less than 1% of all dinucleotides.
The database is designed to collect and analyse thermodynamic, structural and other dinucleotide properties.
This is due to recognition of certain CpG dinucleotide sequences which are immunostimulatory.
The overlapping promoter regions have repeats of the dinucleotide TA in the -10 and -35 sequences.
Other names in common use include 12beta-hydroxy steroid (nicotinamide adenine dinucleotide phosphate), and dehydrogenase.
Interestingly, an initiating dinucleotide does not have the same effect, suggesting that phosphodiester bond formation may be an important requirement in the process (8).
Thus, the two substrates of this enzyme are dinucleotide and HO, whereas its product is mononucleotide.
"What's special about the GpU dinucleotide platform?"
A neutral dinucleotide with Watson-Crick base pairing and a right handed helical twist.
A dinucleotide junction can therefore be described by two letters indicating the two sugar puckers involved (in the conventional 5' 3' direction).
At the DNA level, the halophiles exhibit distinct dinucleotide and codon usage.
This usually occurs at cytosines that form part of a cytosine-guanine dinucleotide (CpG sites).
As mentioned above, only the central step C6pG7 will have B II in both strands at the same dinucleotide level (figure 2, left).
Various footprinting studies have shown that it is selective for the dinucleotide GpC [3-5].
Due to a dinucleotide deletion in the 3FTx gene, toxicity of the snakes' venom was greatly reduced.
This results in elimination of a dinucleotide from each of the 3'ends of the LTR.
It is unclear, however, whether dinucleotide or tetranucleotide STRPs are superior in this regard.
In terms of the wedge model, groove-directed curvature is a result of roll angle contributions of dinucleotide steps (1,6,21).
These results indicate that interactions beyond the dinucleotide level can be important for the prediction of wedge angles and DNA curvature.
Our results thus indicate the importance of interactions beyond the dinucleotide steps in predictive models of DNA curvature.
The presently available data point towards the general conclusion that conformational interactions beyond the dinucleotide steps have an impact on DNA curvature.