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Mitoplasts were obtained by incubation of mitochondria with digitonin 100 g/mg protein (17).
Digitonin is sometimes confused with the cardiac drug digoxin (sometimes also called digitalis or digitoxin), but has no heart-related effects.
All values are expressed as percent LDH released relative to the value obtained following permeabilization of the cells with 50 μM digitonin.
Digitonin is a glycoside obtained from Digitalis purpurea; the aglycone is digitogenin, a spirostan steroid.
All foxgloves are highly toxic if eaten because they contain various cardiac glycosides such as digitoxin, digitalin, digitonin, digitalosmin, gitoxin and gitalonin.
Chiral resolution of this racemic compound with digitonin produced chiral 28 and on Oppenauer oxidation chiral 29.
The seeds of "Digitalis ciliata" are rich in the steroid glycoside Digitonin, along with other lipids that are important in cardiac treatments.
The same, or a closely similar substance, is found in soapwort (Saponaria officinalis), in senega root (Polygala senega) and in sarsaparilla; it appears to be chemically related to digitonin, which occurs in digitalis.
The conversion of cholestenone into cholesterol by the method of Dauben and Eastham (1950) consisted of reduction of the enol acetate (lithium aluminum hydride) and fractionation with digitonin for the isolation of the correct isomer.