desmoplasia

Desmoplasia is thought to have a number of underlying causes.

In medicine, desmoplasia is the growth of fibrous or connective tissue.

Desmoplasia refers to growth of dense connective tissue or stroma.

In addition, tenascin C is found extensively in pancreatic tumor desmoplasia as well.

This is distinguished from desmoplasia in the organization of the tissue, the appendages, and orientation of blood vessels.

Desmoplasia is usually only associated with malignant neoplasms, which can evoke a fibrosis response by invading healthy tissue.

In addition, histopathologic features such as large cell variant, anaplasia, and desmoplasia have been shown in retrospective analyses to correlate with outcome.

In neoplastic diseases, it is called Desmoplasia which is associated with secondary hypoperfusion resulting in characteristic tumor hypoxia.

Desmoplasia may occur around a neoplasm, causing dense fibrosis around the tumor, or scar tissue (adhesions) within the abdomen after abdominal surgery.

The immature scars can be distinguished from desmoplasia by immunohistochemical staining of biopsied tumors that will reveal the type and organization of cells present as well as whether recent trauma has occurred to the tissue.