dephosphorylate

This process can be reversed via the activity of protein phosphatases, which act to dephosphorylate these cation channels.

Currently, there is no known mammalian phosphatase to specifically dephosphorylate PtdIns5P.

The phosphorylated Wee1 allows Cdc25 to dephosphorylate Cdk1 and move the cell into mitosis.

Salubrinal is a selective inhibitor of enzymes that dephosphorylate EIF2-alpha.

They can also dephosphorylate other substrates beside phosphatidate therefore are also known as lipid-phosphate phosphatase.

New research is shifting focus and investigating protein phosphatases that subsequently dephosphorylate the protein kinases.

PTP1B can dephosphorylate the phosphotyrosine residues of the activated insulin receptor kinase.

First, immunocomplexed 6His-HA-PP1α was tested for its ability to dephosphorylate phosphorylase a .

Kinases phosphorylate proteins and phosphatases dephosphorylate proteins.

PHLPP's domain structure influences its ability to dephosphorylate its substrates.

A point mutation study suggests that only the first phosphatase domain of PCP-2 is catalytically active and able to dephosphorylate β-catenin.

These poly-phosphate inositol phosphatases dephosphorylate PIP3 to form PIP2.

PTEN acts as a phosphatase to dephosphorylate phosphatidylinositol-3,4,5-triphosphate (PIP3).

For example, PP2A and PP2B are both present in human brain tissue and have the ability to dephosphorylate Ser396.

A recombinant protein with both PCP-2 phosphatase domains was also able to dephosphorylate EGFR.

Our second approach involved testing immunopurified 6His-HA-PP1α for its ability to dephosphorylate the growth suppressor protein pRB.

Having previously reported on the ability of immunocomplexed endogenous PP1 to dephosphorylate pRB [ 20 ] , we followed the same experimental approach.

The enzyme then acts to dephosphorylate other enzymes, such as phosphorylase kinase, glycogen phosphorylase, and glycogen synthase.

To help prevent the depletion of synaptic vesicles the increase in calcium during intense activity can activate calcineurin which dephosphorylate proteins involved in clathrin-mediated endocytosis.

PTP proteins (protein tyrosine phosphatases), which will dephosphorylate tyrosine AA's on regulatory proteins.

Separase initiates the activation of Cdc14 in early anaphase and Cdc14 has been found to dephosphorylate securin, thereby increasing its efficiency as a substrate for degradation.

CDK1 is dephosphorylated primarily through the actions of Cdc25, which can dephosphorylate both the Thr14 and Tyr15 residues of CDK1.

The ability of PTPrho to dephosphorylate BCR was shown to have functional consequences for the normal development of neuronal dendritic arborization.

Because membrane potential can be controlled using patch clamp techniques, placing VSPs in a membrane allows for experimenters to rapidly dephosphorylate substrates of VSPs.

Activated CHK2 phosphorylates phosphatase CDC25A, which is degraded thereupon and can no longer dephosphorylate CDK2-Cyclin, resulting in cell-cycle arrest.