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Enamel begins to demineralize at a pH of 5.5.
As the lesion continues to demineralize, it can turn brown but will eventually turn into a cavitation ("cavity").
In children under six years of age, fluoride becomes incorporated into the development of permanent teeth, making it difficult for acids to demineralize the teeth.
Acids contained in fruit juice, vinegar and soft drinks lower the pH level of the oral cavity which causes the enamel to demineralize.
In the presence of sugar and other carbohydrates, bacteria in the mouth produce acids that can demineralize enamel, dentin, and cementum.
Sugar is a food for several types of bacteria commonly found in the mouth, particularly Streptococcus mutans; when the bacteria metabolize the sugar they create acids in the mouth which demineralize the tooth enamel and can lead to dental caries.
Acidic foods left on the teeth can also demineralise teeth, eventually causing cavities.