delayed graft

This form of recombinant C1-inhibitor also has been given orphan drug status for delayed graft function following organ transplantation and for capillary leakage syndrome.

The device significantly reduces the risk of Delayed Graft Function, even in DCD (donation after cardiac death) organs.

Developments in kidney preservation have yielded a device that pumps cold preservation solution through the kidneys vessels to prevent Delayed Graft Function (DGF) due to ischemia.

Simultaneous deceased donor pancreas and live donor kidney (SPLK) has the benefit of lower rate of delayed graft function than SPK and significantly reduced waiting times, resulting in improved outcomes.

Unlike in kidneys, where delayed graft function simply means a need for dialysis, delayed graft function in livers can be fatal, which is why only controlled donors are used for livers.

The other focus of his lab is to study molecular tools (SNP analysis, gene expression profiling, and differential expression of microRNA) in order to predict or detect complications (e.g. rejection, delayed graft function) after clinical transplantation.