cytogenetic map

Diagrams identifying the chromosomes based on the banding patterns are known as 'cytogenetic maps'.

Genes have been localized on the cytogenetic map through analysis of chromosomal rearrangements and by fluorescence in situ hybridization (FISH) [ 25, 40, 41].

Drosophila heterochromatin is best defined by the cytogenetic map of neuroblast mitotic chromosomes, which resolves 61 heterochromatic bands (h1-h61) by differential staining properties [ 5, 25].

Initially, the cytogenetic map position of a total of 18 BAC/PAC probes were comparatively mapped using fluorescence in situ hybridization (FISH) (data not shown).

To resolve placement errors, we used a relational database to integrate information from several independent maps, including Genemap'99, assembled genomic contigs, and fingerprint, radiation hybrid and cytogenetic maps (see Materials and methods).

Although banding in the proximal regions of the polytene chromosomes is not as distinct as in the euchromatic regions, comparison of the two datasets shows the approximate extent of overlap between the mitotic and polytene cytogenetic maps (Table 1).