cutaneous eruption

More than 1500 different disorders of the skin exist, including cutaneous eruptions ("rashes") and neoplasms.

Herpes zoster manifests as a painful cutaneous eruption in a dermatomal distribution, often preceded by prodromal pain.

Alphavirus infection may be caused by a Sindbis virus infection, and result in a cutaneous eruption of multiple, erythematous, 4- to 4-mm papules.

The cutaneous eruption is at first a collection of papules which become vesicles (first flat, subsequently umbilicated) and then pustules, and finally thick crusts which slough after a certain time, often leaving a pit, or scar.

True serum sickness, a type III hypersensitivity reaction, results in fever, lymphadenopathy, arthralgias,cutaneous eruptions, gastrointestinal disturbances, proteinuria,and significant decreases in serum complement levels; it was originally described after patients were infused with equine immunoglobulins.

Rare side effects include flushing of the face, hyperhidrosis (excessive sweating), cutaneous eruption, arterial hypotension, tachycardia, loss of appetite, jaundice, eosinophilia, thrombopenia, mixed hepatitis, headache, allergic reaction, chronic active hepatitis, and paradoxical aggravation of cerebral vasospasm.