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It is closely related to the costovertebral angle tenderness.
Physical examination may reveal fever and tenderness at the costovertebral angle on the affected side.
The presence of pain is marked as a positive Murphy's punch sign or as costovertebral angle tenderness.
Since the kidney lies directly below this area, known as the costovertebral angle, tapping disturbs the inflamed tissue causing pain.
Pyelonephritis presents with fever, accelerated heart rate, painful urination, abdominal pain radiating to the back, nausea, and tenderness at the costovertebral angle on the affected side.
On physical examination, one may detect neurological symptoms secondary to a stroke or TIA, a bruit over an affected artery (usually appreciated over the costovertebral angle), and diminished distal pulses.