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The thalamic nuclei involved in sensation, and their cortical projections, are discussed below.
During sleep, the thalamus stops relaying sensory information to the brain, however it continues to produce signals that are sent to its cortical projections.
It consists of cortical projection fibers, association fibers and cortical fibers.
This final connection is reinforced by activity in direct cortical projections from the dopaminergic neurons of the VTA.
The Elongator Protein Complex (ELP) is what regulates the growth of cortical projection neurons.
The primate thalamus consists of a matrix of calbindin immunoreactive cells and a superimposed core of parvalbumin immunoreactive cells which may have differential patterns of cortical projections.
By some measures they account for about 10% of the primary motor cortex neurons projecting to the spinal cord or about 2-3% of the total cortical projection to the spinal cord.
It does not innervate nuclei for nerves III, IV, and VI because these are mediated by cortical projections and yoked together by the MLF, medial longitudinal fasciculus.
The problem with using thalamic nuclei as a guide to cortical organization is that primates have a thalamic nucleus, with extensive cortical projections, for which there is no clearly identifiable homologue in other species.