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The procedure unfortunately produced a high rate of corneal degeneration, however, and was soon rejected by the medical community.
In view of this, the more accurate designation of the disease is possibly not dystrophy but corneal degeneration.
Children and adults with this condition can develop cataracts, glaucoma, corneal degeneration (band keratopathy), or vision loss.
It is used as a screening test for many corneal disorders including corneal post-trauma, corneal perforation and corneal degeneration.
The most common indication in this category is pseudophakic bullous keratopathy, followed by keratoconus, corneal degeneration, keratoglobus and dystrophy, as well as scarring due to keratitis and trauma.
Bilateral Salzmann's-like nodular corneal degeneration after Laser in situ keratomileusis imaged with anterior segment OCT and high frequency ultrasound biomicroscopy.
Further pioneer works were those on the marginal corneal degeneration, the posterior vitreous detachment, the measurement of the optic fundi and of the ocular pressure as well as investigations on trachoma and the pathogenesis of glaucoma.