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During septation at the end of anaphase, Cdr2 localizes to the contractile ring.
It is reasonable that the contractile ring may be able to generate greater force than is minimally required.
The position at which the contractile ring assembles is dictated by the mitotic spindle.
Rather than forming a contractile ring, plant cells construct a cell plate in the middle of the cell.
This region also contains the contractile ring actin filaments [ 36 ] .
Eukaryotic cells during cell division construct contractile rings that are mainly composed of an actin-based cytoskeleton.
Using calibrated needles, Rappaport directly measured the force that the contractile ring produced [ 2 ] .
Cytokinesis is mediated by the contractile ring made up of polymers of actin protein called microfilaments.
Adherens junctions may serve as a regulatory module to maintain the actin contractile ring with which it is associated in microscopic studies.
During cellular cleavage, the contractile ring tightens around the cytoplasm of the cell until the cytoplasm is pinched into two daughter cells.
PEs play a role in membrane fusion and in disassembly of the contractile ring during cytokinesis in cell division.
The totality of the contractile ring, the spindle apparatus, microtubules and the dense peripheral material is called the "Fleming body" or "intermediate body".
Animal cells form an actin-myosin contractile ring within the equatorial region of the cell membrane that constricts to form the cleavage furrow.
Animal cell cleavage furrow formation is caused by a ring of actin microfilaments called the contractile ring, which forms during early anaphase.
Myosin is present in the region of the contractile ring as concentrated microfilaments and actin filaments are predominant in this region.
In an animal cell, cytokinesis involves the generation of force in the region of the contractile ring (reviewed in [ 1 ] ).
In animal cells, a cleavage furrow (pinch) containing a contractile ring develops where the metaphase plate used to be, pinching off the separated nuclei.
Phosphatidylethanolamine (PE) has been shown to be present during this time which indicates that is may play a role in movement between the plasma membrane and contractile ring.
Another group found that CB inhibits the ability of HeLa cells to undergo cytokinesis by decomposition of the contractile ring.
A cell machinery example includes common structures such as contractile ring formation formed by both actin and tubulin type structures leading to the same mechanical result of cell division.
The quantitation of amounts of myosin-II that are recruited to the contractile ring is an essential starting point for developing a more detailed but experimentally tractable model for cytokinesis.
A contractile ring, made of non-muscle myosin II and actin filaments, assembles equatorially (in the middle of the cell) at the cell cortex (adjacent to the cell membrane).
We suggest that MHCK-C is recruited to the contractile ring during late cytokinesis to facilitate the orderly removal of excess myosin II from the ring as the furrow ingresses.
During cytokinesis, the protein progressively accumulates in the furrow cortex until the cell completes division, indicating that heavy chain phosphorylation normally facilitates removal of wild type myosin-II from the contractile ring.
Simultaneous with contractile ring assembly during prophase, a microtubule based structure termed the central spindle (or spindle midzone) forms when non-kinetochore microtubule fibres are bundled between the spindle poles.