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Further evidence for a conformational change of the -50 region is given in Fig. 4.
Conformational analysis for the twist form is similar thus leading to the two forms being very close in energy.
Usually they induce a conformational change within the protein structure.
The energy required for conformational changes may give a more precise and quantitative picture.
It was found that these conformational changes may have a very important physiological significance.
The 2,6-dimethylpiperidines are of interest for their conformational properties.
Conformational changes may then occur as the substrate is bound.
The Hsp90 protein can adopt two major conformational states.
The light causes a conformational change in a protein called rhodopsin.
These domains are also thought to mediate subsequent conformational changes.
At this point it undergoes conformational changes, opening the channel.
As a result, a cascade of conformational changes occur in the gp120 and gp41 proteins.
The ratio of the different conformational states is determined by thermal equilibrium.
However, scoring all possible conformational changes is prohibitively expensive in computer time.
The binding caused a conformational change, with unknown effect.
Physically, the native state of a protein is the conformational free energy minimum for the chain.
Binding of calcium causes a conformational change to occur in the protein.
This membrane insertion could only occur with additional conformational changes.
These conformational changes could also lead to pore opening.
The pore may be hindered by small conformational changes in this region.
The active site is buried and requires a conformational change to allow the substrate access.
Thus, this allows the active site to have a "closed" conformation rather than a large conformational change.
The equilibrium can favor either direction depending on ring size and other conformational effects.
Conformational study on neuromuscular blocking drugs is relatively new and developing.
Conformational or structural explanations for histamine release are not clear.