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Delayed-type hypersensitivity responses induced by bovine colostral components.
Immunotherapeutic efficacy of bovine colostral immunoglobulins from a hyperimmunized cow against cryptosporidiosis in neonatal mice.
Colostral protection lasts up to 5 months of age, after which it decreases to an all-time low to increase yet again at about 12 months of age.
Vaccines should be administered several weeks before conception to provide immunity throughout the susceptible period of gestation but after the disappearance of passively acquired colostral antibody, which could interfere with the development of active immunity.