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She remained well clinically to follow up at one year after onset of her colitic symptoms.
The hydrophobicity of isolates did not differ significantly between colitic and control groups nor were there significant differences correlated with disease activity.
In colonic biopsy specimens from normal and colitic controls inappropriate staining is less evident.
In this study, 300 mg bd terra fullonica and 105 mg bd kaolin were effective in reducing systemic endotoxaemia in the colitic rat to concentrations not different from healthy animals.
The significance of 'sticky'E coli in the pathogenesis of ulcerative colitis remains unclear but their presence in stools of colitic patients does not appear to be as a result of treatment.
Significant colon inflammation was induced in the colitic groups compared with the saline treated animals as measured by the colon macroscopic score, colon weight and colon weight/ body weight ratio (p<0.05)(Table II).
Despite the fact that very few reservoirs have been functioning for more than 10 years, cases have been described in which dysplasia and carcinoma have been seen in colitic pouches and adenomas in FAP pouches.
In some studies increased numbers of Escherichia coli have been reported in the faeces of colitic patients in comparison with control groups of patients and isolates from colitics are also more likely to produce haemolysin and necrotoxin.
It also seems probable that cells from inflamed epithelium (colitis) will be more prone to toxicity from cytokines than will cells from control tissue and this may have introduced artefactual abnormalities in dispersed colitic cells.
In contrast with the differences in adhesins and hydrophobicity, the mucosal isolates from colitic patients were more commonly β-haemolytic than were isolates from non-inflammatory bowel disease controls, as has been well documented for faecal isolates from colitics and also for Crohn's disease.