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Coagulation times return to baseline approximately 1 hour following cessation of bivalirudin administration.
The Lee-White coagulation time is still used today as a method of measuring the speed of blood coagulation.
Recommended laboratory blood testing includes: cross matching blood, hemoglobin, hematocrit, platelets, coagulation time, and electrolytes.
Activated clotting time (ACT), also known as activated coagulation time is a test of coagulation.
Laboratory studies may show evidence of hepatic necrosis with elevated AST, ALT, bilirubin, and prolonged coagulation times, particularly an elevated prothrombin time.
The most likely additive to cause trouble is EDTA which will affect the coagulation time assays and by chelating some of the metal ions may interfere with some of the biochemistry results(especially potassium).