clot dissolution
clot lysis

The ELT measures fibrinolysis by clotting the euglobulin fraction (primarily the important fibrinolytic factors fibrinogen, PAI-1, tPA, alpha 2-antiplasmin, and plasminogen) from plasma and then observing the time required for clot dissolution.

The use of water is preferable because water can help with clot lysis.

A role in clot lysis in vivo.

These methods use the same principle as the older technique, but use a spectrophotometer to track clot lysis as a function of optical density.

Furthermore, upon QPD platelet activation, u-PA can be released into forming clots and accelerate clot lysis, resulting in delayed-onset bleeding (12-24hrs after injury).

The lysine analogues are antifibrinolytics that inhibit certain platelet functions and have no effects on the coagulation process; they cannot initiate or accelerate clot formation but will delay clot lysis.

Assay of PAI1, tPA antigen, tPA activity, fibrin and fibrinogen degradation products, and D-dimer showed indirect fibrin clot lysis.

While heparin does not break down clots that have already formed (unlike tissue plasminogen activator), it allows the body's natural clot lysis mechanisms to work normally to break down clots that have formed.

In addition for pancreatic enzymes carboxypeptidase A and B, PCI also inhibits carboxypeptidase R without affecting the activity of carboxypeptidase N in the circulation and have therefore use in thrombolytic therapy (blood clot lysis).