chromosome instability syndrome

The following chromosome instability syndromes are known:

Chromosome instability syndromes are a group of inherited conditions associated with chromosomal instability and breakage.

Lu X, Lane DP: Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

In addition, genetic syndromes in which an individual is predisposed to breakage of chromosomes (chromosome instability syndromes) are frequently associated with increased risk for various types of cancer, thus highlighting the role of somatic aneuploidy in carcinogenesis.